Cutting Edge HBOT Treatments

Research into the next generation of applications for hyperbaric oxygen therapy is consistently yielding promising results for restoring function and improving quality of life. New studies are constantly being created to further explore its potential.

Because research is ongoing, these newest treatment options have not yet been approved by the FDA, a process which takes many years. But because the research results do support HBOT as a viable adjunct treatment, NexGen Hyperbaric is able to offer it as an off-label treatment option for our patients.

It is important to note that off-label treatments may not be covered by insurance. A NexGen Hyperbaric insurance consultant evaluates each case and assists patients with this aspect.

Off-Label Conditions

These are conditions that have shown promising improvement with HBOT therapy, organized by type. Links are to a selection of research relevant to each.

Cardiology & Vascular

  • Atherosclerosis
  • Heart Attack
  • Peripheral Artery Disease


  • Crush Injuries
  • Near Drowning
  • Spinal Cord Injury
  • Sports Injuries

Illness and Infections

  • AIDS/HIV (related chronic fatigue)
  • Audiology
  • Cancer
  • Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
  • Chronic Hepatitis
  • Gastrointestinal Diseases
    • Crohn’s Disease
    • Inflammatory Bowel Disease
    • Ulcerative Colitis
  • Interstitial Cystitis
  • Severe Acute Pancreatitis

Immune and Inflammatory Disorders

  • Lupus
  • Fibromyalgia
  • Rheumatoid Arthritis
  • Rheumatic Diseases
  • Susac Syndrome (related vision loss)

Neurological Illness & Injury

  • Addiction Rehabilitation (brain function recovery from cell death)
  • Alzheimer’s Dementia
  • Complex Regional Pain Syndrome (CPRS)
  • Fetal Alcohol Syndrome
  • Migraine
  • Peripheral Nerve Damage / Regeneration
  • Post Concussive Syndrome
  • Post Traumatic Stress Disorder (PTSD)
  • Stroke – Ischemic
  • Stroke – Hemorrhagic
  • Traumatic Brain Injury (TBI)
  • Vascular Dementia

Ophthalmology (Eyes, Vision)

  • Anterior Segment Ischemia
  • Diabetic Retinopathy
  • Glaucoma
  • Ischemic Optic Neuropathy
  • Macular Degeneration
  • Macular Edema
  • Retinal Artery Occlusion
  • Retinitis Pigmentosa
  • Scleral Necrosis
  • Sickle Cell Hyphema

Orthopedic (Bones)

  • Femoral Head Necrosis
  • Fractures
  • Osteoarthritis
  • Osteoarthrosis

Post Operative

  • Hepatic Thrombosis (following pediatric liver transplantation)
  • Liver Regeneration (in LDLT – Living Donor Liver Transplantation)
  • Oral Surgery (keratinized oral mucosa)
  • Reconstructive Surgery (traumatic injury)

Frequently Asked Questions

The off-label use of HBOT simply means that the FDA has not explicitly approved a particular treatment protocol using HBOT for a given condition. This, however, does not mean that such treatments are unsafe or ineffective.

An approved indication means that the FDA has approved the use of HBOT for the specific condition being treated. However, there are many off-label uses of HBOT because it is effective in treating a wide range of conditions. Learn more about the off-label HBOT uses here.

Many conditions have been treated with off-label hyperbaric therapy. Some of these conditions include:

  • Cardiology & Vascular
  • Sports Injuries
  • Illness and Infections
  • Immune and Inflammatory Disorders
  • Neurological Illness & Injury
  • Ophthalmology (Eyes, Vision)
  • Orthopedic (Bones)
  • Oral Surgery
  • Reconstructive Surgery

The benefits of HBOT can last long after the treatment is completed.

When you undergo HBOT, your body experiences an increase in the production of new red blood cells. These new red blood cells are thicker and more robust than your typical red blood cells and live longer. The average lifespan of a red blood cell is around 120 days. However, after undergoing HBOT, the lifespan of these new red blood cells is extended. This means that the benefits of HBOT can last for up to 8-12 months, depending on the patient’s health and history.

It can be stopped at any time, but it is recommended that you stop treatment under the guidance of a healthcare professional because there are possible side effects associated with HBOT therapy. Your healthcare professional can help you manage these side effects. Additionally, it is essential to remember that HBOT therapy should not be used as a replacement for other treatments or medications that your doctor has prescribed.

Much research suggests hyperbaric oxygen therapy has legitimate medical benefits. For example, it treats conditions like carbon monoxide poisoning, decompression sickness, gas gangrene, and infections effectively. These are FDA- Approved conditions. However, more research is needed to determine the long-term effects of hyperbaric oxygen therapy and whether it is more effective than other treatment options.

Hyperbaric chambers are used to treat a variety of injuries, including:

  • Crush Injuries
  • Near Drowning
  • Spinal Cord Injury
  • Sports Injuries

There is some evidence that HBOT may have anti-inflammatory effects. One study shows that HBOT reduced the levels of inflammatory markers in the blood of patients with chronic obstructive pulmonary disease (COPD). However, more research is needed to determine how HBOT reduces inflammation and whether it benefits other conditions.

Yes, they can. Hyperbaric oxygen therapy can cause injuries if not done correctly. For example, if someone has a fever while in the chamber, it can potentially raise internal pressure and cause harm. There have also been cases where people have had seizures from too much oxygen.

Injuries can range from mild to severe and even fatal. Injuries can also occur if something goes wrong with the equipment while someone is inside the chamber. However, the risk of an injury is very low.

How Can HBOT Help You?

Contact us today to learn more about how NexGen Hyperbaric can help you heal.

The information provided by The Center For Wound Healing & Hyperbaric Medicine LLC & NexGen Hyperbaric LLC does not constitute a medical recommendation. It is intended for informational and educational purposes only, and no claims, either real or implied are being made. Please consult with our physicians or your own physician for a detailed medical evaluation of your own personal and specific health needs and recommendations.
NexGen Hyperbaric